The oldest operating apothecary in the US has treated everyone from Thomas Edison to Mark Twain.

The rough and tumble president's childhood home displays the shirt he was once shot in and the speech that saved him.

The oldest living tree in Manhattan comes shrouded in sinister legend.

This hidden oasis features a stunning view of the Hudson River and the Palisades from a castle-like museum.

Mysterious 500-year-old tapestries depict a unicorn hunt.

Thomas Edison's home and final resting place also boasts an impressive garage, where some of the earliest electric cars are on display.

The proud hometown of an American legend has honored their favorite son with what seems to be a gravestone.

A religious-themed park filled with folk art to bring biblical stories to life that fell into disrepair and now being restored.

"A hideous albatross in the Hudson River Valley."

Retirement home where the actress who played the Wicked Witch of the West passed away.

The best revenge is a five-tiered layer cake of a dwelling.

The largest living museum in the Northeast recreates life from the Early Republic period complete with costumed historians and reenactors.

The inspiration for H.P. Lovecraft's horror stories and Batman's Arkham Asylum is now a condominium complex.

Located just behind a quiet residential neighborhood, this is ground zero for the Salem witchcraft hysteria of 1692.

Memorial of the Salem witchcraft hysteria in the town of Danvers, where it all began.

A historic custom house with ties to George Washington is now a shrine to local nautical history.

The former home of Samuel Clemens and family remembers the happiest period of the author's life.

The author of Uncle Tom's Cabin was neighbors with Mark Twain while living in this Connecticut home.

The tragic tale of the dentist who pioneered the use of anesthesia.

These etchings reveal the history of a long-gone quarantine site.

This tribute to the founding father of the American dictionary originally contained a spelling error.

Journey inside the bowels of this sperm whale sculpture.

One of the U.S. Forest Service's only mansions is outfitted with a dinner table for floating food.

Named the fifth most beautiful building in America in 1885, this former courthouse boasts the best view in the Village.