A spectacular remnant of an Adler and Sullivan masterpiece that was destroyed in 1972.

This historic hotel invented the chocolate brownie.

Each of these gorgeous, intricately decorated rooms is painstakingly crafted to the scale of 1 inch: 1 foot.

The last masonry skyscraper ever built reveals a transitional moment in architectural history.

One-of-a-kind preserved ruins of an abandoned 1880s church in Chicago's Pilsen neighborhood.

This cheerfully-named branch of the Chicago River is the fetid result of years of blood, entrails, and meatpacking waste.

This awkward aquarium sculpture is one of the strangest statues in Chicago.

At Chicago's revered Field Museum, visitors are invited to learn about and literally explore DNA.

An avant garde art museum at the University of Chicago.

A hollow cement depiction of time's inexorable effect on the human body.

What's left of the ruins of the 1893 Columbian Exhibition, or World's Fair, also known as the White City.

One of the largest pieces of scientific equipment ever carried on a NASA space shuttle sits in a Chicago alley.

This bronze sculpture on a former squash court marks the secret origins of the Atomic Age.

This abstract sculpture is rumored to cast a hammer-and-sickle shadow once a year.

This surprising gem is a world-class archeological museum hidden at the University of Chicago.

An actual 1957 Cadillac De Ville, encased in 15 cubic yards of concrete.

The unluckiest U-boat in the entire German fleet is now on display in a Chicago museum.

A 19th-century horse lover's bequest led to the construction of this unique fountain in Chicago.

This $3 million model train takes you through Chicago, Seattle, and the thousands of miles in between.

The site of the first couple's first kiss is commemorated by the most adorable presidential monument ever.