From church to drug den nightclub to gym, few New York buildings have had as many diverse uses as this one

A plaque immortalizes the spot where the early American spy said his famous last words: "I only regret that I have but one life to lose for my country."

Stunningly detailed mosaics in a New York subway station bring life to the Weimaraners of artist William Wegman's work—and to thousands of commutes.

Storage warehouse of the rich and famous.

A forgotten relic from New York's bygone trolley system hides in plain sight under a bridge.

Site of the first pathological and bacteriological research facility in the United States.

A crumbling hospital from the 1850s on Roosevelt Island.

The feral felines of Roosevelt Island have a small army of allies and an abandoned hospital all to themselves.

One of only two commuter aerial tramways in the United States.

The best B-movies filmed on a shoestring budget were born here.

A vibrant, 100-foot-tall mural dedicated to Evelyn Nesbit, the tragic icon of the Gilded Age.

A semi-scholarly approach to sex.

The former hotel where Tesla invented the radio.

A B.Y.O.B. Mexican cantina lives inside one of the last tortilla factories in Brooklyn.

A Wisconsin kitsch palace from the 1930s lives its second life in 21st-century Brooklyn.

An 1883 schoolhouse now home to collective of artists.

Spike Lee's provocative film is officially honored right where it was made, the first time a work of art was used as a secondary street name.

The childhood home of one of America's greatest unsung troubadours still stands in a much changed Brooklyn neighborhood.

Final resting place for the Triangle Shirtwaist fire’s unidentified victims.

An archive and museum with a mind-boggling collection of Shakespeare-related objects.

A pair of pure white felines guard the entrance to a spot of California real estate established as an artist's haven.

From buttons to beads, flounces to fripperies, this textile museum and shop honors the history of needlework.

The second building of its name to occupy this location might be the finest flatiron building in San Francisco.

The historic building's ornate stained glass fixture has survived the devastating 1906 earthquake, ensuing fires, and multiple redevelopment attempts.