John Wayne, Ronald Reagan, and other Hollywood actors have resided in this picturesque Route 66 hotel.

Owned by Native American women, this brewery is a celebration of indigenous culture in the American Southwest.

This museum shaped like an inflating balloon celebrates the sport’s buoyant achievements.

If drivers cross the rumble strip on this stretch of Route 66 at just the right speed it plays "America the Beautiful."

The official atomic museum of the United States explores the explosive and productive history of a much maligned energy source.

Albuquerque found the perfect use for tumbleweeds at Christmastime.

What appears to be a historic cabin nestled within Valles Caldera National Preserve is actually part of an abandoned movie set.

Once a dining hall for boarding school students, this lodge was a popular haunt for nuclear physicists working on the Manhattan Project.

This museum started as a collection of Manhattan Projects and continues to add exhibits as they are declassified.

A small metropolis of Pueblo cave dwellings have been carved right into the hillside of this national monument.

Once a year, the ruins of an ancient village come alive with hundreds of glowing farolitos.

A unique geological area spiked with wind-carved rocks that resemble teepees.

The second largest roadrunner in the world stands 11 feet tall in his West Texas town.

Mysterious glowing orbs float through the desert night.

A Prada store in the West Texas desert that is never open for business.

The second-largest cave chamber in the world was discovered in 1898 by a 16-year-old and a friend known as "Pothead."

A museum dedicated to the alleged Roswell Incident.

A blacklight journey through a celestial art exhibit.

This fast-food outlet is the only space and UFO-themed McDonalds in the world.

The symbol was surreptitiously built into the river bank by German prisoners of war.

The final resting place of the most famous outlaw in the Old West.

A somber monument commemorates the site of a Native American reservation marked by suffering.

A clear blue swimming hole with hidden caves, still unexplored.

Catch two 18-foot-tall ranchers mid-brawl as you drive by on Highway 285.