This bar named after the world's first mixed cocktail was home to one of New Orleans' most notorious politicians.

The oldest family-run restaurant in the United States is a living museum of New Orleans dining history.

The curiosities and wonders of pharmacy in a delightful historic building.

A 200-year-old bar in the historic French Quarter refuses to give up its place in history, nor its role in securing ours.

Located along historic Route 66, this former gas station has been restored and converted into a museum filled with vintage motorcycles.

It reportedly took three years to sort through all the objects in this eclectic lifelong collection.

Where hills of dirt conceal the burial ground of one of the most powerful ancient Native American societies.

This historic folk art garden contains a nightmare tower that claims to be the world's largest concrete totem pole.

The show pony of cave systems, Fantastic Caverns manages to live up to its name.

400 million-year old limestone caverns nestled in the Ozarks served as shelter and a hideout for cultures throughout North American history.

A quirky mishmash of Route 66 memorabilia and other throwbacks from the past.

The only fully-realized skyscraper built by the famed American architect, Frank Lloyd Wright.

Claims to be the "World's Highest Hill."

This small-town museum is dedicated to the original western movie mega-star.

An oil baron's wild paradise and the winner of an ill-fated air race.

A whimsical tower with a spiral staircase, inspired by the Space Age and the Möbius strip.

One of the oldest show caves in Arkansas.

The site of a tragedy in 1908 that claimed the lives of 171 people and changed fire safety laws across the state.

Beautiful views of the surrounding hills and birds of prey can be found at this sanctuary.

This extraordinary Depression-era expenditure was modeled after a postcard of a Mediterranean hotel.

These lush botanical gardens employ the most purrfect pest control force.

This jail which was in service for over a century is now open for curious visitors.

A toxic ghost town sitting atop a massive coal fire.

A daily replay of the experiment that proved the rotation of the Earth.