Kentucky, Tennessee, and Virginia meet at this point in the Cumberland Gap.

An early-19th-century hotel with a past that is steeped in the Civil War.

An out-of-the-way wildlife haven with a rich and storied past of harboring thousands of fugitive slaves, or "Maroons" during the mid 1800s.

A simple but powerful tribute to the 20 victims of the 1692 witch trials.

A collection of full-size movie monsters opened to the public.

An innovative attempt to break a siege in the American Civil War still scars the earth today.

A home that witnessed Civil War combat on the Sunken Road has the battle scars to prove it.

An early life spent in this "Old Kentucky Home" inspired the writings of North Carolina's most famous novelist.

This Transylvania County city is home to a rare white squirrel population that is descended from an escaped carnival animal.

A walk down memory lane in the heart of one of San Francisco's most notorious neighborhoods.

Enormous lake at the bottom of a unique cave system.

Once connected to the outside world by a single train track, this ghost town is looked after by the National Park Service.

This "second" cemetery represents New Orleans' attempt to keep cholera at bay.

A collection of oddities including Dr. Kevorkian's suicide device, the Thanatron.

Once the site of a Native American harvest festival, this humble clearing later played an invaluable role in the birth of jazz.

South Carolina's last remaining slavery auction house is now a museum devoted to its own tragic history.

Colloquially known as "the lynching memorial," this is the United States' first memorial to the victims of racial terror at home.

This high point in the Great Smoky Mountains is said to be home to the chief of all bears.

The highest point in North Carolina and the United States east of the Mississippi River, Mount Mitchell is named after argumentative explorer Elisha Mitchell.

A wonderful display of arts and crafts handmade by local artisans in the Southern Appalachians.

This shifting North Carolina sand dune is an odd little desert surrounded by oceanic forest life.

A 56-foot tall statue of the god of fire looks out over Birmingham, Alabama.

Knoxville’s architectural icon was the symbol of the 1982 World’s Fair, even catching the googly eye of Bart Simpson.

A snapshot of the city's fascinating voodoo culture.