A Civil War Museum with some notable medical antiques.

This advertisement for talcum powder was painted on the rock face and has since defied removal.

One of the oldest anatomical theaters in the U.S. still in use was once the site of an infamous cadaver riot.

Baltimore's classic clock tower was once topped by a rotating, 20-ton medicine bottle.

Once America's tallest structure, now a Baltimore landmark.

This bug-eyed water wheel uses the power of the Sun to clean up Baltimore Harbor.

George Washington's dentures and Queen Victoria's dental instruments are in the nation’s official museum of the dental profession.

This simple convenience store sits on the location where the Ouija board was named—and has a plaque to prove it.

A museum dedicated to exhibiting remarkable outsider art.

The trials and tribulations of marking Poe’s grave.

It’s not hard to see why the historic Peabody Conservatory of Music’s library has been described as a “cathedral of books.”

The residents of this ominous-sounding street in Pennsylvania liked its name so much they fought to keep it.

This giant disembodied horse head seems to balance impossibly on its nose.

A daily replay of the experiment that proved the rotation of the Earth.

A favorite of Amelia Earhart, ranking among those rare bridges that can be crossed without changing sides of the river.

One of the three perfect vellum copies of this historic book known to exist is on display in a specially-designed case.

This shifting North Carolina sand dune is an odd little desert surrounded by oceanic forest life.

Established in 1937, the oldest candy shop in New York City boasts a rainbow-colored inventory that would make Willy Wonka envious.

You don't have to be an ambassador to dine like one.

This lavish room in a New York City mansion is a rare relic from the end of the Gilded Age.

Hundreds of numbered stakes hidden in the woods mark the graves of the lost souls of a nearby asylum.

A way to take your secrets to someone else's grave.

What happens here stays here – unless it affects the whole world.

Decades after testing the polio vaccine on unwitting patients, this historic mental hospital sits in ruin.