Bootleggers ran booze beneath this building before (and after) Route 66 appeared beside it.

An incredible airplane graveyard sits outside this small museum dedicated to preserving aviation history.

An homage to everyone's favorite prehistoric cartoon family.

This small museum is dedicated to the study of coprolites, or fossilized poop.

The final resting place of the businessman-turned-astronomer who helped discover Pluto stands near his observatory.

This Arizona observatory is famous for investigations into Martian life, and as the place humans first spotted Pluto.

A planet-hunting astrograph built in the 1920s to seek out the so-called "Planet X" beyond Uranus.

The world's only teal arches exist in a city that cares more about its aesthetic than an Instagram influencer.

Ninety feet off the valley floor is an ancient dwelling put under protection of the U.S. government by Teddy Roosevelt.

A spiritual vortex among the red rocks in Sedona.

This oversized flute-playing Ancestral Puebloan deity is also a landmark of Southwestern kitsch.

A Bibliophile's Dream.

To find the "unicorns of the deep" you've got to go downstairs.

Once at the center of U.S. finance, the historic Trading Room was meticulously recreated piece by piece and rebuilt in the Art Institute.

Beloved bar home to musicians of all eras and reputations.

What may be America's largest classic video game arcade lurks inconspicuously in a Chicago suburb.

Take in the beauty of the Milky Way at one of the best sites for stargazing in Nevada—a state with some tough competition.

A stretch of highway even lonelier than the so-called "Loneliest Road in America."

An errant donkey ushered in a new era of mining in Nevada.

This sign designates the road that leads to the infamous Area 51.

Mysterious meeting place for UFO hunters near Area 51.

An eatery for UFO seekers on the Extraterrestrial Highway.

Stepping away from the glitz of mobsters and casinos to learn about the other history of Vegas.

In the middle of a remote desert town is a surprisingly opulent hotel.