John Wayne, Ronald Reagan, and other Hollywood actors have resided in this picturesque Route 66 hotel.

In 1967, murder and mayhem disrupted the tranquility along this quiet stretch of Old Route 66.

Owned by Native American women, this brewery is a celebration of indigenous culture in the American Southwest.

The old Route 66 town straddling Texas and New Mexico died along with the Main Street of America.

The collection is housed in an exquisite mansion that makes you feel like you've been transported to an Italian villa.

It reportedly took three years to sort through all the objects in this eclectic lifelong collection.

When you can afford only half a road, you build only half a road.

What was meant to be a temporary exhibit is now a permanent fixture at the St. Louis Zoo filled with beautiful birds.

One of the world's earliest skyscrapers.

A creepy sculpture of a decapitated head invites viewers to see St. Louis through its empty eyes.

A plaque on the side of a parking garage marks the burial place of a great Ottawa chief.

The Old Courthouse takes visitors on a captivating trip through St. Louis' timeline.

The surprising home of the iconic Santa Monica Pier Ferris Wheel.

This water tower slanted at an uncomfortable angle off the old Route 66 was an ingenious marketing ploy.

A small car graveyard sits in the shadow of the famous Cadillac Ranch.

A sculpture made of 10 Cadillacs as a monument to the “Golden Age” of the American automobile.

This sanguine boulevard was named after a deadly cowboy bar fight.

Giant steel and concrete dinosaurs near Route 66 invite passerbys into a mineral shop.

This abandoned bootleg attraction was built to cash in on the popularity of classic TV show, F Troop.

One of Frank Lloyd Wright's greatest—and favorite—architectural masterpieces was almost lost.

This 24-acre park offers a place for meditation in the midst of Sedona's iconic red rocks.

A replica of the flagpole that gave a frontier town its name.

A mysterious "wedding cake" castle in the middle of the urban desert.

Millions of years of erosion created the feature for which this rock formation is aptly named.